Implementation of Genome Transposition in GRIMM

We are thankful to Almighty Allah for his blessings for the successful completion of our thesis. Our heartiest gratitude, profound indebtedness and deep respect go to our supervisor Prof. Dr. M.SohelRahman,DepartmentofCSE,BangladeshUniversityofEngineeringand Technology, Dhaka, Bangladesh, for his co...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Noor, Rafi Imran, Alam, Nabila Binte, Ahmed, Saroar
বিন্যাস: গবেষণাপত্র
ভাষা:ইংরেজি
প্রকাশিত: Department of Computer Science and Engineering, Military Institute of Science and Technology 2015
বিষয়গুলি:
অনলাইন ব্যবহার করুন:http://hdl.handle.net/123456789/98
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author Noor, Rafi Imran
Alam, Nabila Binte
Ahmed, Saroar
author_browse Ahmed, Saroar
Alam, Nabila Binte
Noor, Rafi Imran
author_facet Noor, Rafi Imran
Alam, Nabila Binte
Ahmed, Saroar
author_sort Noor, Rafi Imran
collection DSpace
description We are thankful to Almighty Allah for his blessings for the successful completion of our thesis. Our heartiest gratitude, profound indebtedness and deep respect go to our supervisor Prof. Dr. M.SohelRahman,DepartmentofCSE,BangladeshUniversityofEngineeringand Technology, Dhaka, Bangladesh, for his constant supervision, affectionate guidance and great encouragement and motivation. His keen interest on the topic and valuable advices throughout the study was of great help in completing thesis. We are especially grateful to the Department of Computer Science and Engineering (CSE) of Military Institute of Science and Technology (MIST) for providing their all out support during the thesis work. Finally, we would like to thank our families and our course mates for their appreciable assistance, patience and suggestions during the course of our thesis.
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publishDate 2015
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publisher Department of Computer Science and Engineering, Military Institute of Science and Technology
publisherStr Department of Computer Science and Engineering, Military Institute of Science and Technology
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spelling oai:localhost:123456789-982015-06-28T04:58:19Z Implementation of Genome Transposition in GRIMM Noor, Rafi Imran Alam, Nabila Binte Ahmed, Saroar Genome, Transposition, GRIMM, Genome, We are thankful to Almighty Allah for his blessings for the successful completion of our thesis. Our heartiest gratitude, profound indebtedness and deep respect go to our supervisor Prof. Dr. M.SohelRahman,DepartmentofCSE,BangladeshUniversityofEngineeringand Technology, Dhaka, Bangladesh, for his constant supervision, affectionate guidance and great encouragement and motivation. His keen interest on the topic and valuable advices throughout the study was of great help in completing thesis. We are especially grateful to the Department of Computer Science and Engineering (CSE) of Military Institute of Science and Technology (MIST) for providing their all out support during the thesis work. Finally, we would like to thank our families and our course mates for their appreciable assistance, patience and suggestions during the course of our thesis. InComputationalbiology,genomerearrangementbytranspositionisanimportantproblem. Genome evolution analysis by transpositions leads to a combinatorial optimization problem of sorting by transpositions. Though the status of the transposition distance problem was open, a non-trivial proof for the NP-completeness of the transposition median problem is given [2]. In this paper, we utilize a 1.375-approximation algorithm for sorting by transpositions [16]. GRIMM is a tool for analyzing rearrangements in pairs of genomes, including unichromosomal and multichromosomal genomes, and signed and unsigned data. In GRIMM, reversal is the only operation for unichromosomal genome rearrangement. In this paper, we implement transposition in GRIMM as another unichromosomal operation. Wealsocomputethetranspositionaldistancebetweentwogenomesandcomputeitwiththe corresponding reversal distance. At the end of the paper, we also show that, we merge, two algorithms [16] and [11], we reduced the algorithm [16] in our implementation of transposition. Department of Computer Science and Engineering 2015-06-25T07:48:32Z 2015-06-25T07:48:32Z 2013-12 Thesis http://hdl.handle.net/123456789/98 en B.Sc. in Computer Science and Engineering Thesis; application/pdf Department of Computer Science and Engineering, Military Institute of Science and Technology
spellingShingle Genome, Transposition, GRIMM, Genome,
Noor, Rafi Imran
Alam, Nabila Binte
Ahmed, Saroar
Implementation of Genome Transposition in GRIMM
title Implementation of Genome Transposition in GRIMM
title_full Implementation of Genome Transposition in GRIMM
title_fullStr Implementation of Genome Transposition in GRIMM
title_full_unstemmed Implementation of Genome Transposition in GRIMM
title_short Implementation of Genome Transposition in GRIMM
title_sort implementation of genome transposition in grimm
topic Genome, Transposition, GRIMM, Genome,
url http://hdl.handle.net/123456789/98
work_keys_str_mv AT noorrafiimran implementationofgenometranspositioningrimm
AT alamnabilabinte implementationofgenometranspositioningrimm
AT ahmedsaroar implementationofgenometranspositioningrimm